Johanna P. Müller

01 Research

Research

I build self-supervised and supervised AI that finds rare diseases and under-represented anatomies without labelled examples, working closely with clinicians to make it trustworthy enough for the clinic.

01 Statement

Medical-imaging AI has matured quickly under conditions that hold in a handful of large hospitals: abundant labelled data, a narrow set of imaging protocols, and dense clinician and engineer collaboration. Most of my work asks what happens when those conditions don't hold: when a finding is rare enough that no one has labelled an example of it, when a scanner or protocol differs from the one a model was trained on, or when a clinician needs to know how much to trust a prediction rather than just receiving one.

Five Topics

01

Anomaly & out-of-distribution detection

I build methods that find rare or unexpected findings in medical images without labelled abnormal examples, including confidence-aware self-supervised localisation and zero-shot pipelines built on pre-trained segmentation models.

02

Uncertainty quantification

A point prediction without a confidence signal has limited clinical use. I develop Laplace-approximation-based methods, including L-FUSION for fetal ultrasound segmentation, that give clinicians an interpretable measure of how much to trust a given output.

03

Generative modelling

Some anatomy is chronically under-represented in training data. I build diffusion-based synthesis pipelines, for female pelvic MRI and separately for label-free cardiac ultrasound, that generate realistic training and benchmark data where real examples are scarce.

04

Data- & resource-efficient learning

Small-cohort and low-resource settings can't always afford backpropagation-heavy training. I've explored alternatives including Forward-Forward networks.

05

Clinical applications

Methods only matter if they hold up on real clinical questions. I collaborate directly with clinical groups on lymphatic perfusion in Fontan patients, pancreas segmentation in diabetes, and axillary lymph-node metastasis prediction, work that keeps the other four threads honest about what a hospital actually needs.

Two placements in international medical-imaging challenges (winner of the MOOD Challenge in 2023 and 2024 including 5-year GOAT prize, third place at the VAND Challenge in 2023) within amazing teams.

03 Workshops & proceedings

Organising and editing

2026

Co-Organiser

MICCAI CAPI & WOMEN Workshop (Computer-Aided Pelvic Imaging for Female Health)

2025

Co-Organiser & Editor

MICCAI 1st International Workshop on Computer-Aided Pelvic Imaging for Female Health (CAPI), Daejeon, South Korea

Edited proceedings, with the 10th International Workshop on Skin Image Analysis (ISIC 2025): Skin Image Analysis, and Computer-Aided Pelvic Imaging for Female Health, Springer Nature. Co-edited with M. E. Celebi, C. Barata, A. Halpern, P. Tschandl, M. Combalia, and others, including M. May.

2023

Co-Organiser & Editor

MICCAI 4th International Workshop on Advances in Simplifying Medical Ultrasound (ASMUS), Vancouver, Canada

Edited proceedings: Simplifying Medical Ultrasound, Springer Nature LNCS vol. 14337. Co-edited with B. Kainz, A. Noble, J. Schnabel, B. Khanal, and T. Day.

04 Reviewing

Reviewing for

  • MICCAI and associated workshops
  • IEEE Transactions on Medical Imaging (TMI)
  • Journal of Machine Learning for Biomedical Imaging (MELBA)
  • International Joint Conference on Artificial Intelligence (IJCAI)
MICCAI Outstanding Reviewer Award '26

05 Output

Selected papers

MICCAI ’26

Fibers of Asymmetric Similarity: A Framework for Clinical and Imaging Data

Müller JP, Baugh M, Wright R, Day T, Rezavi R, Kainz B

MICCAI · 2026

@inproceedings{muller2026fibers,
  title     = {Fibers of Asymmetric Similarity: A Framework for
               Clinical and Imaging Data},
  author    = {M{\"u}ller, Johanna P. and Baugh, M. and Wright, R.
               and Day, T. and Rezavi, R. and Kainz, B.},
  booktitle = {MICCAI},
  year      = {2026}
}
ASMUS ’25

L-FUSION: Laplacian Fetal Ultrasound Segmentation and Uncertainty Estimation

Müller JP, Wright R, Day T, Venturini L, Budd S, Reynaud H, Hajnal J, Razavi R, Kainz B

Simplifying Medical Ultrasound, ASMUS 2025, eds. Ni D, Noble A, Huang R, Xue W, Springer LNCS vol. 16165, Cham

@inproceedings{muller2026lfusion,
  title     = {L-FUSION: Laplacian Fetal Ultrasound Segmentation and
               Uncertainty Estimation},
  author    = {M{\"u}ller, Johanna P. and Wright, Robert and Day, Thomas G. and Venturini, Lorenzo and Budd, Samuel F. and Reynaud, Hadrien and Hajnal, Joseph V. and Razavi, Reza and Kainz, Bernhard},
  editor    = {Ni, D. and Noble, A. and Huang, R. and Xue, W.},
  booktitle = {Simplifying Medical Ultrasound},
  series    = {Springer LNCS},
  volume    = {16165},
  address   = {Cham},
  year      = {2026},
  note      = {ASMUS 2025}
}
CAPI ’25

Diffusing the Blind Spot: Uterine MRI Synthesis with Diffusion Models

Müller JP, Knupfer A, Blöss P, Vittur EB, Kainz B, Hutter J

MICCAI CAPI Workshop · 2025

@inproceedings{muller2026diffusing,
  title     = {Diffusing the Blind Spot: Uterine MRI Synthesis with
               Diffusion Models},
  author    = {M{\"u}ller, Johanna P. and Knupfer, A. and Bl{\"o}ss, P.
               and Vittur, E. B. and Kainz, B. and Hutter, J.},
  editor    = {Celebi, M. E. and others},
  booktitle = {Skin Image Analysis, and Computer-Aided Pelvic Imaging
               for Female Health},
  series    = {Springer LNCS},
  volume    = {16149},
  address   = {Cham},
  year      = {2025},
  note      = {CAPI 2025}
}
AAAI ’24

Trade-offs in Fine-Tuned Diffusion Models Between Accuracy and Interpretability

Dombrowski M, Reynaud H, Müller JP, Baugh M, Kainz B

Proceedings of the AAAI Conference on Artificial Intelligence, 38(19):21037–21045 · 2024

@inproceedings{dombrowski2024tradeoffs,
  title     = {Trade-offs in Fine-Tuned Diffusion Models Between
               Accuracy and Interpretability},
  author    = {Dombrowski, M. and Reynaud, H. and M{\"u}ller,
               Johanna P. and Baugh, M. and Kainz, B.},
  booktitle = {Proceedings of the AAAI Conference on Artificial
               Intelligence},
  volume    = {38},
  number    = {19},
  pages     = {21037--21045},
  year      = {2024},
  month     = mar
}
UNSURE ’23

Confidence-Aware and Self-supervised Image Anomaly Localisation

Müller JP, Baugh M, Tan J, Dombrowski M, Kainz B

International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging, pp. 177–187, Cham: Springer Nature Switzerland · 2023

Introduces confidence-aware self-supervised localisation for detecting rare or unexpected findings in medical images without labelled abnormal examples. Part of the line of work that won the MICCAI Medical Out-of-Distribution (MOOD) Challenge in 2023 and 2024.
@inproceedings{muller2023confidenceaware,
  title     = {Confidence-Aware and Self-supervised Image Anomaly
               Localisation},
  author    = {M{\"u}ller, Johanna P. and Baugh, M. and Tan, J.
               and Dombrowski, M. and Kainz, B.},
  booktitle = {International Workshop on Uncertainty for Safe
               Utilization of Machine Learning in Medical Imaging},
  publisher = {Springer Nature Switzerland},
  address   = {Cham},
  pages     = {177--187},
  year      = {2023},
  month     = oct
}
MICCAI ’23

Many Tasks Make Light Work: Learning to Localise Medical Anomalies from Multiple Synthetic Tasks

Baugh M, Tan J, Müller JP, Dombrowski M, Batten J, Kainz B

International Conference on Medical Image Computing and Computer-Assisted Intervention, pp. 162–172, Cham: Springer Nature Switzerland · 2023

@inproceedings{baugh2023many,
  title     = {Many Tasks Make Light Work: Learning to Localise
               Medical Anomalies from Multiple Synthetic Tasks},
  author    = {Baugh, M. and Tan, J. and M{\"u}ller, Johanna P.
               and Dombrowski, M. and Batten, J. and Kainz, B.},
  booktitle = {International Conference on Medical Image Computing
               and Computer-Assisted Intervention},
  publisher = {Springer Nature Switzerland},
  address   = {Cham},
  pages     = {162--172},
  year      = {2023},
  month     = oct
}